I know of more than a couple of porky pigs that thought it was just a bit too much ! I'd stay away from the 180's (good deer load though) and stick with 240's or 300's.
Here is a little report on how different ammo wil make a huge difference. I went to the range today to check out my Ruger 96 44 mag and try a few different brands of ammo. Thus far I had only used UMC 180's for Fla pigs. They did just fine, but remember my shots were in the 15-25 yds range.
25yd 50 yd 100yd (all 3 shot groups)
UMC180 JSP 3" 7" Didn't even try
Blazer 240 JSP Completely missed 8 1/2 x 11 paper @ 25yds
Win 240 JSP 3/4" 1 3/4" 2 1/2"
Amazing results. I'm glad I tried all three before I went afield.