I love my Rem. 700 .22-250 for coyotes. We had mange come through hard and I was never too concerned with fur hunting, just predator management for the last 5 years. But at the end of last year I had some luck killing some nice furry coyotes. I had been using .45gr hollow point loads that seemed to go off like a grenade on impact, which is fine when knocking down mangy dogs. I know a .22-250 is a little heavy as far as fur hunting goes, but does anyone have a grain and bullet style combination in .22-250 that they would recommend to help me save a little fur this winter?